Heather Watson blamed nerves as she made a first-round exit at the US Open for the fifth straight year.
2014 runner-up Kei Nishikori suffered a shock exit on day one of the US Open, losing to Frenchman Benoit Paire in five sets.
Ana Ivanovic was the first major casualty of the US Open as she fell 6-3 3-6 6-3 to Dominika Cibulkova.
Coverage of the US Open's opening day at Flushing Meadows as Heather Watson and Kei Nishikori are knocked out - watch live on Sky Sports 1 HD.
Former US Open champion Mats Wilander says Andy Murray's body language is still a key weakness against the top players.
Our Andy Schooler picks out his best bets for day one of the US Open at Flushing Meadows.
Our Andy Schooler says Andy Murray is primed to win a second US Open title.
Grand Slam-seeking Serena Williams should be opposed at the US Open, says Andy Schooler, who is backing Simona Halep.
You can stream selected US Open matches live on your mobile device with Sky Bet. No bet required, just a Sky Bet account!
Check out all the singles and doubles draws for the US Open 2015, updated regularly each day and including live scores